Towbin J A, Vatta M, Li H
Department of Pediatrics (Cardiology), Texas Children's Hospital and Baylor College of Medicine, Houston 77030, USA.
J Electrocardiol. 2000;33 Suppl:11-22. doi: 10.1054/jelc.2000.20361.
This article outlines the up-to-date understanding of the molecular basis of primary ventricular arrhythmias. Two disorders have recently been well described at the molecular level, the long QT syndromes and Brugada syndrome, and this article reviews the current scientific knowledge of each disease. A third disorder, arrhythmogenic right ventricular dysplasia, which is on the cusp of understanding, will also be described.
本文概述了对原发性室性心律失常分子基础的最新认识。最近在分子水平上对两种疾病进行了详细描述，即长QT综合征和Brugada综合征，本文将回顾每种疾病的当前科学知识。还将描述第三种疾病——致心律失常性右室心肌病，这种疾病正处于被认识的边缘。
