Upwardly mobile proteins. Workshop: the role of HMG proteins in chromatin structure, gene expression and neoplasia.
作者信息
Bianchi M E, Beltrame M
机构信息
DIBIT, San Raffaele Research Institute, Milano, Italy.
出版信息
EMBO Rep. 2000 Aug;1(2):109-14. doi: 10.1093/embo-reports/kvd030.
Abstract
摘要
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本文引用的文献
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Differential in vivo modifications of the HMGI(Y) nonhistone chromatin proteins modulate nucleosome and DNA interactions.HMGI(Y) 非组蛋白染色质蛋白在体内的差异修饰调节核小体与 DNA 的相互作用。
Biochemistry. 2000 Jul 18;39(28):8333-46. doi: 10.1021/bi000378+.
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Binding of HMG-I(Y) imparts architectural specificity to a positioned nucleosome on the promoter of the human interleukin-2 receptor alpha gene.HMG-I(Y) 的结合赋予人白细胞介素-2 受体α基因启动子上定位核小体结构特异性。
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Mechanism for specificity by HMG-1 in enhanceosome assembly.HMG-1在增强体组装中特异性的机制。
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Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin.类固醇激素诱导HMG1过表达，并使乳腺癌细胞对顺铂和卡铂敏感。
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Protein zero gene expression is regulated by the glial transcription factor Sox10.蛋白零基因的表达受神经胶质转录因子Sox10调控。
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Acetylation of novel sites in the nucleosomal binding domain of chromosomal protein HMG-14 by p300 alters its interaction with nucleosomes.p300对染色体蛋白HMG - 14核小体结合域中新位点的乙酰化作用改变了其与核小体的相互作用。
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