Wolf W, Baltzer J, Schekatz E, Lohe K J
Geburtshilfe Frauenheilkd. 1975 Jan;35(1):37-9.
Among 280 patients with carcinoma in-situ of the uterine cervix treated from 1961 to 1970, a review of the histology revealed 50 patients in which the carcinoma in-situ had been removed with certainty by conization. None of these patients was found to have had a recurrence. In the literature, 13 observations of a recurrence of carcinoma in-situ after complete removal by conization were located among 3, 129 cases. It is concluded that true recurrence after complete removal of carcinoma in-situ by conization is rare and that conization is adequate treatment for carcinoma in-situ for patients who attend regular follow-up examinations.