Brygge T, Heinig J H, Collins P, Ronborg S, Gehrchen P M, Hilden J, Heegaard S, Poulsen L K
Allergy Unit National University Hospital, National University Hospital, Copenhagen, Denmark.
Respir Med. 2001 Mar;95(3):173-9. doi: 10.1053/rmed.2000.0975.
Many asthma patients seek alternative or adjunctive therapies. One such modality is reflexology, whereby finger pressure is applied to certain parts of the body. The aim of the study was to examine the popular claim that reflexology treatment benefits bronchial asthma. Ten weeks of active or simulated (placebo) reflexology given by an experienced reflexologist, were compared in an otherwise blind, controlled trial of 20+20 outpatients with asthma. Objective lung function tests (peak flow morning and evening, and weekly spirometry at the clinic) did not change. Subjective scores (describing symptoms, beta2-inhalations and quality of life) and also bronchial sensitivity to histamine improved on both regimens, but no differences were found between groups receiving active or placebo reflexology. However, a trend in favour of reflexology became significant when a supplementary analysis of symptom diaries was carried out. It was accompanied by a significant pattern compatible with subconscious unblinding, in that patients tended to guess which treatment they had been receiving. No evidence was found that reflexology has a specific effect on asthma beyond placebo influence.
许多哮喘患者寻求替代疗法或辅助疗法。其中一种方法是反射疗法，即对身体的某些部位施加指压。该研究的目的是检验反射疗法对支气管哮喘有益这一普遍说法。在一项针对20+20名哮喘门诊患者的单盲对照试验中，比较了由经验丰富的反射疗法师进行的为期十周的主动反射疗法或模拟（安慰剂）反射疗法。客观肺功能测试（早晚峰值流量以及每周在诊所进行的肺活量测定）没有变化。两种治疗方案的主观评分（描述症状、β2吸入剂使用情况和生活质量）以及支气管对组胺的敏感性均有所改善，但接受主动反射疗法或安慰剂反射疗法的组之间未发现差异。然而，在对症状日记进行补充分析时，支持反射疗法的趋势变得显著。这伴随着一种与潜意识非盲法相符的显著模式，即患者倾向于猜测自己接受的是哪种治疗。没有证据表明反射疗法除了安慰剂影响之外对哮喘有特定作用。
