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一例涉及“非商用”石棉的混合粉尘暴露异常病例。

An unusual case of mixed-dust exposure involving a "noncommercial" asbestos.

作者信息

Dodson R F, Levin J L

机构信息

Department of Cell Biology and Environmental Sciences, The University of Texas Health Center at Tyler, Texas, USA.

出版信息

Environ Health Perspect. 2001 Feb;109(2):199-203. doi: 10.1289/ehp.01109199.

Abstract

Our health center evaluated an individual for suspected pneumoconiosis, which had resulted from exposures in a foundry/metal reclamation facility. Appropriate consent forms were obtained for the procedures. Historically, individuals who work in foundries have been exposed to various types of dusts. The clinical findings in this case were consistent with silicosis with a suspicion of asbestos-induced changes as well. A sample from this individual, analyzed by electron microscopy, showed both classical and atypical ferruginous bodies. The uncoated fiber burden in this individual indicated an appreciable number of anthophyllite asbestos fibers. This finding, coupled with analysis of cores from ferruginous bodies and the presence of ferruginous bodies in areas of interstitial fibrosis, pathologically supported the diagnosis of asbestos-related disease. The unique factor associated with this case is that unlike in some settings in Finland where anthophyllite was mined and used commercially, this mineral fiber is not commonly found in commercially used asbestos products in the United States. Although the actual source of the asbestos exposure in this case is still being sought, it should be recognized that anthophyllite is a contaminant of many other minerals used in workplace environments, including foundries. The fiber burden indicates a unique type of exposure, differing from that usually construed as typical in occupational settings in the United States.

摘要

我们的健康中心对一名疑似患有尘肺病的个体进行了评估,该疾病是由在铸造厂/金属回收设施中的接触所致。已获取该程序的适当同意书。从历史上看,在铸造厂工作的个体曾接触过各种类型的粉尘。该病例的临床发现与矽肺病相符,同时也怀疑有石棉所致的改变。通过电子显微镜对该个体的样本进行分析,发现了典型和非典型的含铁小体。该个体未涂层的纤维负荷表明存在相当数量的直闪石石棉纤维。这一发现,再加上对含铁小体核心的分析以及间质纤维化区域中含铁小体的存在,从病理学上支持了石棉相关疾病的诊断。与该病例相关的独特因素是,与芬兰某些开采和商业使用直闪石的情况不同,这种矿物纤维在美国商业使用的石棉产品中并不常见。尽管仍在寻找该病例中石棉接触的实际来源,但应该认识到直闪石是工作场所环境中使用的许多其他矿物的污染物,包括铸造厂。纤维负荷表明了一种独特的接触类型,与美国职业环境中通常所认为的典型接触不同。

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