Coronary arteries with chronic rejection contain oligoclonal T cells: persistence of clonally expanded T cell receptor transcripts from the early posttransplantation period through chronic rejection. - Suppr | 超能文献

Coronary arteries with chronic rejection contain oligoclonal T cells: persistence of clonally expanded T cell receptor transcripts from the early posttransplantation period through chronic rejection.

作者信息

Slachta C A, Jeevanandam V, Goldman B, Lin W L, Platsoucas C D

机构信息

Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

出版信息

Transplant Proc. 2001 Feb-Mar;33(1-2):452-5. doi: 10.1016/s0041-1345(00)02091-1.

DOI:10.1016/s0041-1345(00)02091-1

Abstract

摘要

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Coronary arteries with chronic rejection contain oligoclonal T cells: persistence of clonally expanded T cell receptor transcripts from the early posttransplantation period through chronic rejection.

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Coronary arteries from human cardiac allografts with chronic rejection contain oligoclonal T cells: persistence of identical clonally expanded TCR transcripts from the early post-transplantation period (endomyocardial biopsies) to chronic rejection (coronary arteries).具有慢性排斥反应的人类心脏同种异体移植的冠状动脉含有寡克隆T细胞：从移植后早期（心内膜活检）到慢性排斥反应（冠状动脉），相同的克隆性扩增TCR转录本持续存在。

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T cells infiltrating coronary arteries of cardiac allografts with chronic rejection contain clonally expanded T lymphocytes.浸润慢性排斥反应心脏移植冠脉的T细胞含有克隆性扩增的T淋巴细胞。

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