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与动脉粥样硬化相关的良性胆管狭窄

Benign biliary stricture associated with atherosclerosis.

作者信息

Saiura A, Umekita N, Inoue S, Maeshiro T, Miyamoto S, Matsui Y, Asakage M, Kawahara Y, Kitamura M

机构信息

Department of Surgery, Tokyo Bokuto Metropolitan Hospital, Tokyo, Japan.

出版信息

Hepatogastroenterology. 2001 Jan-Feb;48(37):81-2.

Abstract

We report a case of benign bile duct stricture that could not be differentiated from intrahepatic bile duct carcinoma preoperatively. The patient was a 79-year-old man. Computed tomography showed dilatation of the intrahepatic bile duct in the left lobe. Direct cholangiography showed segmental stricture of the left bile duct. Angiography showed narrowing of the left hepatic artery. Although bile cytology did not show malignant cells, we suspected intrahepatic bile duct carcinoma preoperatively. We performed extended left hepatic lobectomy. Histopathologic examination of the resected duct also showed no malignant cells; fibrosis with infiltration by lymphocytes was seen at the bile duct stricture. In addition, the resected liver specimen showed sclerotic change in the intrahepatic arteries. The postoperative course was uneventful for more than 26 months, without recurrence or cholangitis. We encountered a very rare case of benign segmental bile duct stricture, which was difficult to differentiate from bile duct carcinoma. We think the biliary stricture was secondary to atherosclerosis which may have caused bile duct ischemia.

摘要

我们报告一例术前无法与肝内胆管癌相鉴别的良性胆管狭窄病例。患者为一名79岁男性。计算机断层扫描显示左叶肝内胆管扩张。直接胆管造影显示左胆管节段性狭窄。血管造影显示左肝动脉变窄。尽管胆汁细胞学检查未发现恶性细胞,但我们术前怀疑为肝内胆管癌。我们实施了扩大左肝叶切除术。切除胆管的组织病理学检查也未发现恶性细胞;在胆管狭窄处可见伴有淋巴细胞浸润的纤维化。此外,切除的肝脏标本显示肝内动脉有硬化改变。术后26个多月病情平稳,无复发或胆管炎。我们遇到了一例非常罕见的良性节段性胆管狭窄病例,很难与胆管癌相鉴别。我们认为胆管狭窄是动脉粥样硬化继发的,可能导致了胆管缺血。

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