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[阿片系统在酒精依赖形成机制中的作用]

[Role of opiate system in mechanisms of formation of alcohol-dependence].

作者信息

Kharchenko N K

机构信息

Ukrainian Scientific Research Institute of Social and Forensic Psychiatry, Ukrainian Ministry of Public Health, Kyiv, Ukraine.

出版信息

Fiziol Zh (1994). 2000;46(5):9-13.

PMID:11269860
Abstract

Effect of naloxon on the activity of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in the blood serum and content of catecholamines (CA) in the brain structures (hypothalamus, midbrain, new cortex) and blood of rats under alcoholic dependence were studied. Participation of opiate structures of receptors in formation of alcoholic dependence is shown.

摘要

研究了纳洛酮对酒精依赖大鼠血清中乙醇脱氢酶（ADH）和乙醛脱氢酶（ALDH）的活性以及脑结构（下丘脑、中脑、新皮层）和血液中儿茶酚胺（CA）含量的影响。结果表明阿片受体结构参与了酒精依赖的形成。

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