Boleas Aguirre M S, Toledo G, Cervera-Paz F J, Okafor O, García-Tapia Urrutia R
Departamento de Otorrinolaringología, Clínica Universitaria, Universidad de Navarra, Avda. Pío XII, no. 36, 31008 Pamplona.
Acta Otorrinolaringol Esp. 2001 Jan-Feb;52(1):80-3. doi: 10.1016/s0001-6519(01)78182-4.
Metastatic involvement of the laryngeal is very rare, with around 150 cases reported to the literature. In eight of these cases, the primary tumor was a colon adenocarcinoma. We report the case of a 80 year-old woman treated of a colloid adenocarcinoma of 7 years earlier, referred to us for chronic and progressive dyspnea. Endoscopic examination showed a subglottic spherical mass, which caused an important compromise of the respiratory airway. Tomographic studies revealed also a thyroid mass. The patient was treated with a tracheostomy, resection of the subglottic mass (with intraoperative diagnosis of "mucin producing tumor"), and total thyroidectomy. The final pathologic diagnosis of the subglottic mass was a metastasis of colloid adenocarcinoma of the colon. In the literature reviewed there are no previous reports of metastatic involvement of the larynx with this type of colon adenocarcinoma. We discuss the clinical and radiological findings, and therapeutic options for metastasis to the larynx, as well as pathological differential diagnosis.
喉转移瘤非常罕见，文献报道约150例。其中8例的原发肿瘤为结肠腺癌。我们报告一例80岁女性病例，该患者7年前曾接受黏液腺癌治疗，因慢性进行性呼吸困难转诊至我院。内镜检查显示声门下有一球状肿物，导致呼吸道严重受压。断层扫描研究还发现甲状腺有肿物。患者接受了气管切开术、声门下肿物切除术（术中诊断为“黏液产生性肿瘤”）及甲状腺全切除术。声门下肿物的最终病理诊断为结肠黏液腺癌转移。在所查阅的文献中，此前尚无关于此类结肠腺癌喉转移的报道。我们讨论了临床和影像学表现、喉转移瘤的治疗选择以及病理鉴别诊断。
