Natera-Rey G, Borges G, Medina-Mora Icaza M E, Solís-Rojas L, Tiburcio-Sainz M
Departamento de Investigaciones Psicosociales, Instituto Nacional de Psiquiatría (INP) Ramón de la Fuente Muñiz, México, D.F., México.
Salud Publica Mex. 2001 Jan-Feb;43(1):17-26.
To assess the risk for alcohol abuse among individuals with a positive family history of alcohol abuse (FH+).
The study population was a sample (n = 8,890) drawn from a 1988 national survey on addictions in Mexico City's urban population. Data analysis consisted of frequency and association measures, using family history of alcohol abuse as the exposure factor.
Prevalence of heavy drinking was 13.7% for males and 0.6% for females. Alcohol dependence syndrome was found in 9.9% of males and 0.6% of females. Men with HF+ were twice more likely to develop dependence syndrome than HF- males. The odds ratio for women was 1.27.
Differential patterns by gender were found for familial transmission of alcohol abuse; parental alcohol intake is a main risk factor for developing alcohol dependence syndrome.
评估有酒精滥用家族史（FH+）的个体发生酒精滥用的风险。
研究人群是从1988年墨西哥城城市人口成瘾情况全国调查中抽取的一个样本（n = 8890）。数据分析包括频率和关联度量，将酒精滥用家族史作为暴露因素。
男性重度饮酒患病率为13.7%，女性为0.6%。男性酒精依赖综合征患病率为9.9%，女性为0.6%。有FH+的男性发生依赖综合征的可能性是无FH+男性的两倍。女性的比值比为1.27。
发现酒精滥用的家族传播存在性别差异模式；父母饮酒是发生酒精依赖综合征的主要危险因素。
