Anatomical evidence for cone and rod-like receptors in the gray squirrel, ground squirrel, and prairie dog retinas.

In the gray squirrel (Sciurus carolinensis), the prairie dog (Cynomys ludovicianus), and the Mexican and 13-line ground squirrels (Citellus mexicanus and C. tridecemlineatus) there exist two distinct classes of photo-receptors that have cone-like and rod-like anatomical features respectively. These two receptor classes were previously known to exist in the gray squirrel, but only the cone-like (C) receptor had been observed in the other species. We have now found small numbers of rod-like (R) receptors in the other species as well. R-receptors comprise about 40% of the receptors in the gray squirrel, 10% of the receptors in the prairie dog, and 4-5% of the receptors in the two species of ground squirrel. This paper describes certain light and electron microscopic features of these two receptor classes including their synaptic connections with second-order cells and with each other. We find that the C-receptor has a morphology and synaptic organization characteristic of other mammalian cones. However, the R-receptor differs from other mammalian rods in certain morphological respects, and its synaptic organization has both cone and rod characteristics as well as some unusual features.