Lundkvist K, Olsen L
Akademiska barnsjukhuset, Uppsala.
Lakartidningen. 2001 Jan 24;98(4):322-6.
82 children with gastroesophageal reflux, 43 of whom were seriously neurologically impaired, were operated according to Nissen. A retrospective study compares the results, complications and recurrences between children with and children without neurological disability. There were no major differences between the groups; four of the neurologically impaired children and one without impairment had died from unrelated causes. In 62 children, 31 of whom were neurologically impaired, the operation was completely successful, 13 children (six of whom were neurologically impaired) had minor problems, two (both neurologically impaired) had major problems. The conclusion is that serious neurological impairment can not be considered a contraindication to antireflux surgery.
82例胃食管反流患儿，其中43例存在严重神经功能障碍，按照nissen术式进行手术。一项回顾性研究比较了有神经功能障碍和无神经功能障碍儿童之间的手术结果、并发症及复发情况。两组之间无显著差异；4例有神经功能障碍的儿童和1例无神经功能障碍的儿童死于无关原因。62例患儿手术完全成功，其中31例存在神经功能障碍；13例患儿（其中6例存在神经功能障碍）有轻微问题，2例（均存在神经功能障碍）有严重问题。结论是严重神经功能障碍不能被视为抗反流手术的禁忌证。
