与氯吡格雷相关的致命性再生障碍性贫血。

Fatal aplastic anaemia associated with clopidogrel.

作者信息

Trivier J M, Caron J, Mahieu M, Cambier N, Rose C

出版信息

Lancet. 2001 Feb 10;357(9254):446. doi: 10.1016/S0140-6736(00)04015-0.

Abstract

Clopidogrel, an inhibitor of platelet aggregation, was initially thought to be free of the side-effects of ticlopidine. We describe a man who developed aplastic anaemia after 5 months of treatment with clopidogrel. There were no other plausible causes. We suggest that his fatal aplastic anaemia might have been induced by clopidogrel.

摘要

氯吡格雷是一种血小板聚集抑制剂，最初被认为没有噻氯匹定的副作用。我们描述了一名男性，在接受氯吡格雷治疗5个月后发生了再生障碍性贫血。没有其他合理的病因。我们认为他的致命性再生障碍性贫血可能是由氯吡格雷诱发的。