甲状腺对小肠氧消耗的调控以及钠离子、氧分压、葡萄糖和麻醉的影响。
Thyroid control of small intestinal oxygen consumption and the influence of sodium ions, oxyhen tension, glucose and anaesthesia.
作者信息
Levin F J, Syme G
出版信息
J Physiol. 1975 Feb;245(1):271-87. doi: 10.1113/jphysiol.1975.sp010845.
Abstract
- Oxygen consumption of jejunum removed from either killed or anaesthetized euthytoid, hypothyroid and triiodothyronine (T3)-treated rats was measured polarographically in vitro. 2. Hypothyroidism induced by drinking 6-n-propyl-2-thiouracil depressed jejunal oxygen consumption. 3. Treatment of euthyroid rats with T3 stimulated jejunal oxygen consumption by 39% in the presence of 28 mM glucose and by 23% in its absence. 4. Sodium ions appear to play a major permissive role in the action of T3 on jejunal oxygen uptake. In the presence of sodium, T3 stimulated significantly the oxygen consumption by 23% while in the absence of sodium the stimulation was only 10% which was not significant. The sodium-sensitive oxygen uptake of the jejunum was expanded by 57% after T3 treatment.
摘要
- 采用极谱法在体外测定了从处死或麻醉的甲状腺功能正常、甲状腺功能减退及三碘甲状腺原氨酸（T3）处理的大鼠身上取下的空肠的氧消耗量。2. 饮用6-正丙基-2-硫氧嘧啶诱导的甲状腺功能减退降低了空肠的氧消耗量。3. 用T3处理甲状腺功能正常的大鼠，在有28 mM葡萄糖存在时，空肠氧消耗量增加39%，在无葡萄糖时增加23%。4. 钠离子似乎在T3对空肠氧摄取的作用中起主要的允许作用。在有钠离子存在时，T3显著刺激氧消耗量增加23%，而在无钠离子时，刺激仅为10%，无统计学意义。T3处理后，空肠对钠离子敏感的氧摄取增加了57%。
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本文引用的文献
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