Santolaria S, Cabezali R, Ortego J, Castiella T, Salinas J C, Lanas A
Service of Gastroenterology, University Hospital Lozano Blesa, Zaragoza, Spain.
J Clin Gastroenterol. 2001 Apr;32(4):344-6. doi: 10.1097/00004836-200104000-00014.
Diaphragm-like strictures of the small bowel are an infrequent complication of the treatment of patients with nonsteroidal antiinflammatory drugs (NSAIDs).
We report a patient with this condition in whom the use of NSAIDs was ruled out by both clinical history and objective blood testing of current aspirin use.
He reported a history of recurrent episodes of colic abdominal pain during the past 25 years; he underwent three surgical operations for this condition. Before these symptoms, he had an undefined abdominal process with diarrhea, weight loss, and diffuse edema, which resolved spontaneously without reaching a diagnosis.
We suggest that diaphragm-like strictures might be developed as a nonspecific response to different damaging insults to the intestine and are not necessarily associated with NSAID use.
小肠隔膜样狭窄是非甾体抗炎药(NSAIDs)治疗患者中罕见的并发症。
我们报告了一名患有这种疾病的患者,通过临床病史和当前阿司匹林使用情况的客观血液检测排除了NSAIDs的使用。
他报告在过去25年中有反复出现的绞痛性腹痛病史;为此他接受了三次外科手术。在出现这些症状之前,他有一个不明原因的腹部病变,伴有腹泻、体重减轻和弥漫性水肿,该病变未经诊断便自行缓解。
我们认为,隔膜样狭窄可能是对肠道不同损伤性刺激的一种非特异性反应,不一定与NSAIDs的使用有关。