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升主动脉粥样硬化——心脏外科医生面临的一个复杂且具有挑战性的问题。

Ascending aortic atherosclerosis--a complex and challenging problem for the cardiac surgeon.

作者信息

Bonatti J

机构信息

Innsbruck University Hospital, Division of Cardiac Surgery, University of Innsbruck, Austria.

出版信息

Heart Surg Forum. 1999;2(2):125-35.

Abstract

Ascending aortic atherosclerosis is an increasingly recognized problem in cardiac surgery. It is the most important risk factor for perioperative stroke and seems to be in part responsible for postoperative neurobehavioral changes. Patients exhibiting ascending aortic atherosclerosis have a significantly reduced survival rate and are at considerable risk for spontaneous embolic stroke during the long-term postoperative course. Preoperative noninvasive diagnosis and intraoperative assessment by inspection or palpation of the aorta are insensitive. Intraoperative epiaortic ultrasound scanning has emerged as a most helpful tool for the diagnosis of ascending aortic atherosclerosis and has revealed major insights into the nature and distribution of this disease. Management strategies range from minimally invasive aortic "no touch" techniques to maximally invasive procedures, including application of deep hypothermic circulatory arrest. Operative modifications in coronary artery bypass grafting include avoidance of aortic crossclamping, alternative methods of aortic crossclamping and placement of all arterial in situ bypass conduits, Y-grafts or extra-anatomical bypass grafts. Other operative strategies include modifications of the arterial cannulation site, replacement of the ascending aorta or ascending aortic endarterectomy. One of the most recently developed methods is embolic capture by intraaortic filters. Increased awareness of ascending aortic atherosclerosis is critical in order to prevent the devastating complications it can cause during cardiac surgery.

摘要

升主动脉粥样硬化是心脏外科中一个日益受到重视的问题。它是围手术期卒中最重要的危险因素,而且似乎在一定程度上导致了术后神经行为改变。患有升主动脉粥样硬化的患者生存率显著降低,并且在术后长期过程中发生自发性栓塞性卒中的风险相当高。术前通过非侵入性诊断以及术中通过检查或触诊主动脉进行评估的方法并不敏感。术中经食管超声心动图扫描已成为诊断升主动脉粥样硬化最有用的工具,并对该疾病的性质和分布有了重要的认识。治疗策略从微创主动脉“非接触”技术到最大程度的侵入性手术,包括应用深低温停循环。冠状动脉旁路移植术中的手术改良包括避免主动脉阻断、替代主动脉阻断方法以及放置所有原位动脉旁路移植血管、Y型移植物或解剖外旁路移植血管。其他手术策略包括改变动脉插管部位、置换升主动脉或升主动脉内膜切除术。最近开发的方法之一是使用主动脉内滤器捕获栓子。提高对升主动脉粥样硬化的认识对于预防其在心脏手术期间可能导致的灾难性并发症至关重要。

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