Chun H J, Doty J R, Salazar J D, Richmond J, Fonger J D
Division of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Heart Surg Forum. 1999;2(3):230-4.
Assessment of graft patency following minimally invasive direct coronary artery bypass (MIDCAB) surgery is essential in order to determine the efficacy of this technique. This study was conducted to evaluate the role of intraoperative and postoperative noninvasive flow and velocity measurements to follow and predict graft performance.
Between April 1996 and July 1997, 130 patients had 133 grafts placed using MIDCAB techniques. Intraoperative transit-time ultrasound was used to assess graft patency and flow prior to wound closure. Also, serial transcutaneous doppler examinations were performed to evaluate graft patency on the first postoperative day, at two weeks, and at three months. Peak values for systolic and diastolic waveforms were measured for both flow and velocity, and the diastolic-to-systolic ratio was calculated at each time interval. Recatheterization was performed selectively for inadequate ultrasound flow or doppler velocity, or for patient symptoms.
Seven (5.3 %) grafts developed stenosis or occlusion. When compared to normal grafts, mean intraoperative flows, flow ratios, and velocity ratios were lower. Mean postoperative diastolic peak velocity (DPV) to systolic peak velocity (SPV) ratio remained stable over time for normal grafts; however, grafts with stenosis or occlusion demonstrated a diminished DPV/SPV ratio.
Intraoperative transit-time ultrasound and outpatient transcutaneous doppler examinations did not reach a predictive value for graft stenosis or occlusion following MIDCAB surgery in this series of patients. However, these data demonstrate trends that may help identify patients at an increased risk for unfavorable events, guiding the use of postoperative recatheterization in such patients.
评估微创直接冠状动脉旁路移植术(MIDCAB)后的移植物通畅情况对于确定该技术的疗效至关重要。本研究旨在评估术中和术后无创血流及速度测量在监测和预测移植物性能方面的作用。
1996年4月至1997年7月期间,130例患者采用MIDCAB技术植入了133个移植物。术中使用经渡越时间超声在伤口闭合前评估移植物通畅情况和血流。此外,在术后第一天、两周和三个月进行系列经皮多普勒检查以评估移植物通畅情况。测量血流和速度的收缩期和舒张期波形峰值,并在每个时间间隔计算舒张期与收缩期比值。对于超声血流或多普勒速度不足或患者出现症状的情况,选择性地进行再次导管检查。
7个(5.3%)移植物出现狭窄或闭塞。与正常移植物相比,术中平均血流、血流比值和速度比值较低。正常移植物术后舒张期峰值速度(DPV)与收缩期峰值速度(SPV)的平均比值随时间保持稳定;然而,出现狭窄或闭塞的移植物DPV/SPV比值降低。
在这一系列患者中,术中经渡越时间超声和门诊经皮多普勒检查对于MIDCAB术后移植物狭窄或闭塞未达到预测价值。然而,这些数据显示出一些趋势,可能有助于识别发生不良事件风险增加的患者,指导对此类患者术后再次导管检查的应用。