N-氨基吲哚啉衍生物作为5-脂氧合酶抑制剂
N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase.
作者信息
Audouin C, Mestdagh N, Lassoie M A, Houssin R, Hénichart J P
机构信息
Institut de Chimie Pharmaceutique Albert Lespagnol, Université de Lille 2, France.
出版信息
Bioorg Med Chem Lett. 2001 Mar 26;11(6):845-8. doi: 10.1016/s0960-894x(01)00077-4.
Abstract
N-Aminoindoline derivatives were prepared and their 5-lipoxygenase inhibitory activities were evaluated in vitro and compared with those of phenidone and NDGA. Compound 4 presents the most effective 5-LO inhibition.
摘要
制备了N-氨基吲哚啉衍生物，并在体外评估了它们的5-脂氧合酶抑制活性，并与非那宗和去甲二氢愈创木酸的活性进行了比较。化合物4表现出最有效的5-脂氧合酶抑制作用。
Zotero 插件