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妊娠期间复发性转移性输卵管癌

Recurrent metastatic fallopian tube carcinoma in pregnancy.

作者信息

Adolph A, Le T, Khan K, Biem S

机构信息

Department Obstetrics, Gynecology and Reproductive Sciences, Royal University Hospital, Saskatoon, Saskatchewan, S7N 0W0, Canada.

出版信息

Gynecol Oncol. 2001 Apr;81(1):110-2. doi: 10.1006/gyno.2000.6097.

Abstract

BACKGROUND

Fallopian tube cancer is the rarest of all gynecologic cancers. An extensive literature search on Medline reveals no previous case reports of fallopian tube carcinoma in association with a term pregnancy.

CASE

A woman with surgical stage IIB fallopian tube carcinoma was treated with limited staging laparotomy, as per the patient's fertility wishes, followed by adjuvant cis-platinum and paclitaxel (Taxol). One year following chemotherapy, she conceived. She was noted to have an asymptomatic intraabdominal recurrence at 16 weeks. The patient completed 37 weeks of pregnancy without further therapy according to her wishes. She subsequently underwent a cesarean section with optimal tumor reduction surgery. Carboplatin and paclitaxel were reinstituted, achieving partial response. She is presently alive with stable disease status 6 months after completing her salvage chemotherapy.

CONCLUSION

This is the first case report of recurrent fallopian tube cancer in pregnancy.

摘要

背景

输卵管癌是所有妇科癌症中最罕见的。对医学在线数据库(Medline)进行广泛文献检索后发现,此前尚无输卵管癌合并足月妊娠的病例报告。

病例

一名患有手术分期为IIB期输卵管癌的女性,根据患者的生育意愿,接受了有限分期剖腹探查术,随后进行辅助性顺铂和紫杉醇(泰素)治疗。化疗一年后,她怀孕了。在孕16周时发现她有无症状的腹腔内复发。患者按照自己的意愿在未接受进一步治疗的情况下完成了37周的妊娠。随后她接受了剖宫产及最佳肿瘤减灭术。重新使用卡铂和紫杉醇治疗后,病情获得部分缓解。在完成挽救性化疗6个月后,她目前仍存活,病情稳定。

结论

这是首例妊娠合并复发性输卵管癌的病例报告。

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