Ahlqvist G, Landin S, Wroblewski R
Lab Invest. 1975 May;32(5):673-9.
Ultrastructural studies of muscle biopsies from the vastus lateralis of the quadriceps in seven patients with Parkinson's disease and six patients with upper motor lesions are presented. All patients showed varying degrees of mitochondrial changes. Loss of outer membranes or abnormal inner membranes were observed alone or in combination. A reduced number of mitochondria was also noted in some cases. A disorder of filaments was seen. It is assumed that the mitochondrial changes are connected with the altered oxidative capacity previously observed in these patients.
本文呈现了对7例帕金森病患者和6例上运动神经元损伤患者股四头肌外侧肌活检组织的超微结构研究。所有患者均表现出不同程度的线粒体变化。单独或合并观察到线粒体外膜缺失或内膜异常。在某些病例中还发现线粒体数量减少。可见细丝紊乱。据推测，线粒体变化与先前在这些患者中观察到的氧化能力改变有关。
