Forna F, Gülmezoglu A M
Department of Gynecology and Obstetrics, Emory University School of Medicine, 69 Butler Street, S.E., Atlanta, Georgia 30303, USA.
Cochrane Database Syst Rev. 2001(1):CD001993. doi: 10.1002/14651858.CD001993.
Incomplete abortion is a major problem that should be effectively managed with safe and appropriate procedures. Surgical evacuation of the uterus for management of incomplete abortion usually involves vacuum aspiration or sharp curettage.
To compare the safety and effectiveness of surgical uterine evacuation methods for management of incomplete abortion.
We searched the Cochrane Pregnancy and Childbirth Group trials register, Medline from 1966, Popline from 1970, and the Cochrane Controlled Trials Register. Trials were also identified from reference lists of reviews. Date of last search: October 2000.
Randomized trials where different surgical methods were used to manage incomplete abortion were eligible for inclusion.
We extracted population characteristics, settings, and exclusion criteria, in addition to outcomes such as complications of the procedure, duration, need for re-evacuation, blood transfusion, and analgesia/anesthesia.
Two trials were included. Vacuum aspiration was associated with statistically significantly decreased blood loss (-17 mls weighted mean difference, 95% confidence interval (CI) -24 to -10 mls), less pain (relative risk (RR): 0.74, 95% CI 0.61, 0.90), and shorter duration of procedure (-1.2 minutes weighted mean difference, 95% CI -1.5 to -0.87 minutes), than sharp curettage, in the single study that evaluated these outcomes. Serious complications such as uterine perforation and other morbidity were rare and the sample sizes of the trials were not large enough to evaluate small or moderate differences.
REVIEWER'S CONCLUSIONS: Vacuum aspiration is safe, quick to perform, and less painful than sharp curettage, and should be recommended for use in the management of incomplete abortion. Analgesia and sedation should be provided as necessary for the procedure.
不全流产是一个重大问题,需要通过安全且恰当的程序进行有效处理。通过手术清空子宫来处理不全流产通常采用真空吸引术或刮宫术。
比较用于处理不全流产的手术清空子宫方法的安全性和有效性。
我们检索了Cochrane妊娠与分娩组试验注册库、1966年起的Medline、1970年起的Popline以及Cochrane对照试验注册库。还从综述的参考文献列表中识别出试验。最后检索日期:2000年10月。
使用不同手术方法处理不全流产的随机试验符合纳入标准。
除了诸如手术并发症、持续时间、再次清空的必要性、输血以及镇痛/麻醉等结果外,我们还提取了人群特征、研究背景和排除标准。
纳入了两项试验。在评估这些结果的单一研究中,与刮宫术相比,真空吸引术在统计学上显著减少了失血量(加权平均差为-17毫升,95%置信区间(CI)-24至-10毫升),疼痛较轻(相对风险(RR):0.74,95%CI 0.61,0.90),且手术持续时间较短(加权平均差为-1.2分钟,95%CI -1.5至-0.87分钟)。子宫穿孔等严重并发症及其他发病率较低,且试验样本量不足以评估微小或中等差异。
真空吸引术安全、操作迅速且比刮宫术疼痛轻,应推荐用于处理不全流产。手术过程中应根据需要提供镇痛和镇静。