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帕金森病患者物理治疗技术的比较

A comparison of physiotherapy techniques for patients with Parkinson's disease.

作者信息

Deane K H, Jones D, Ellis-Hill C, Clarke C E, Playford E D, Ben-Shlomo Y

出版信息

Cochrane Database Syst Rev. 2001(1):CD002815. doi: 10.1002/14651858.CD002815.

Abstract

BACKGROUND

Despite optimal medical and surgical therapies for Parkinson's disease, patients develop progressive disability. The role of the physiotherapist is to maximise functional ability and minimise secondary complications through movement rehabilitation within a context of education and support for the whole person. What form of physiotherapy is most effective in the treatment of Parkinson's disease remains unclear.

OBJECTIVES

  1. To compare the efficacy and effectiveness of novel physiotherapy techniques versus 'standard' physiotherapy in patients with Parkinson's disease. Standard physiotherapy is defined as the type of therapy that the physiotherapist would usually use to treat Parkinson's disease. 2. To compare the efficacy and effectiveness of one physiotherapy technique versus a second form of physiotherapy.

SEARCH STRATEGY

Relevant trials were identified by electronic searches of MEDLINE, EMBASE, CINAHL, ISI-SCI, AMED, MANTIS, REHABDATA, REHADAT, GEROLIT, Pascal, LILACS, MedCarib, JICST-EPlus, AIM, IMEMR, SIGLE, ISI-ISTP, DISSABS, Conference Papers Index, Aslib Index to Theses, the Cochrane Controlled Trials Register, the CentreWatch Clinical Trials listing service, the metaRegister of Controlled Trials, ClinicalTrials.gov, CRISP, PEDro, NIDRR and NRR; and examination of the reference lists of identified studies and other reviews.

SELECTION CRITERIA

Only randomised controlled trials (RCT) were included.

DATA COLLECTION AND ANALYSIS

Data was abstracted independently by KD and CEH and differences settled by discussion.

MAIN RESULTS

Seven trials were identified with 142 patients. All used small numbers of patients and the method of randomisation and concealment of allocation was poor or not statedin all of the trials. These methodological problems could potentially lead to bias from a number of sources. The methods of physiotherapy varied so widely that the data could not be combined.

REVIEWER'S CONCLUSIONS: Considering the small number of patients examined, the methodological flaws in many of the studies and the possibility of publication bias, there is insufficient evidence to support or refute the efficacy of any given form of physiotherapy over another in Parkinson's disease. Another Cochrane review, Physiotherapy for patients with Parkinson's Disease, found that there was insufficient evidence to support or refute the efficacy of physiotherapy compared to no physiotherapy in Parkinson's disease. A wide range of physiotherapy approaches were used in these studies and a survey of UK physiotherapists confirmed that they also use an eclectic combination of techniques in the treatment of Parkinson's disease (Plant 1999). Therefore a consensus must be found as to 'best practice' physiotherapy for Parkinson's disease. The efficacy of 'standard' physiotherapy should be proved first before examining variations in physiotherapy methods. Therefore large well designed randomised controlled trials are needed to judge the effect of physiotherapy in Parkinson's disease. After this large RCTs are needed to demonstrate the most effective form of physiotherapy in Parkinson's disease. Outcome measures with particular relevance to patients, carers, physiotherapists and physicians should be chosen and the patients monitored for at least 6 months to determine the duration of any effect. The trials should be reported according to CONSORT guidelines (CONSORT 1996).

摘要

背景

尽管针对帕金森病有最佳的药物和手术治疗方法,但患者仍会出现进行性残疾。物理治疗师的作用是在对患者进行全面教育和支持的背景下,通过运动康复最大限度地提高功能能力并减少继发并发症。目前尚不清楚哪种形式的物理治疗对帕金森病的治疗最有效。

目的

  1. 比较新型物理治疗技术与“标准”物理治疗对帕金森病患者的疗效和效果。标准物理治疗定义为物理治疗师通常用于治疗帕金森病的治疗类型。2. 比较一种物理治疗技术与另一种物理治疗形式的疗效和效果。

检索策略

通过对MEDLINE、EMBASE、CINAHL、ISI - SCI、AMED、MANTIS、REHABDATA、REHADAT、GEROLIT、Pascal、LILACS、MedCarib、JICST - EPlus、AIM、IMEMR、SIGLE、ISI - ISTP、DISSABS、会议论文索引、阿思利布学位论文索引、Cochrane对照试验注册库、CenterWatch临床试验列表服务、对照试验元注册库、ClinicalTrials.gov、CRISP、PEDro、NIDRR和NRR进行电子检索,识别相关试验;并查阅已识别研究和其他综述的参考文献列表。

入选标准

仅纳入随机对照试验(RCT)。

数据收集与分析

KD和CEH独立提取数据,差异通过讨论解决。

主要结果

共识别出7项试验,涉及142名患者。所有试验纳入的患者数量均较少,且所有试验中随机化和分配隐藏的方法都很差或未说明。这些方法学问题可能会导致来自多个来源的偏差。物理治疗方法差异很大,因此数据无法合并。

综述作者结论

鉴于所研究的患者数量较少、许多研究存在方法学缺陷以及存在发表偏倚的可能性,没有足够的证据支持或反驳在帕金森病中任何一种特定形式的物理治疗优于另一种的疗效。另一篇Cochrane综述《帕金森病患者的物理治疗》发现,没有足够的证据支持或反驳与不进行物理治疗相比,物理治疗在帕金森病中的疗效。这些研究中使用了广泛的物理治疗方法,对英国物理治疗师的一项调查证实,他们在帕金森病治疗中也使用多种技术的综合方法(Plant,1999年)。因此,必须就帕金森病的“最佳实践”物理治疗达成共识。在研究物理治疗方法的差异之前,应首先证明“标准”物理治疗的疗效。因此,需要进行大型的精心设计的随机对照试验来判断物理治疗在帕金森病中的效果。在此之后,需要进行大型随机对照试验来证明帕金森病中最有效的物理治疗形式。应选择与患者、护理人员、物理治疗师和医生特别相关的结局指标,并对患者进行至少6个月的监测,以确定任何效果的持续时间。试验应按照CONSORT指南(CONSORT,1996年)进行报告。

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