Kulkarni M G, Kavishwar V S, Chogle A R, Parab V V, Aigal U, Koppikar G V
TN Medical College, Mumbai-8.
J Assoc Physicians India. 2000 Dec;48(12):1160-3.
To analyse clinicopathological features of HIV infected patients admitted in an infectious disease hospital in Mumbai.
Retrospective study of 501 patients admitted from 1st September, 1996 to 28th February, 1998 and screened for HIV status out of clinical suspicion was carried out. HIV seropositivity was established by double confirmation of spot test results with microwell Elisa test.
HIV seropositivity was seen in 39.92%. Out of these 94% were adults with male preponderance and 96.5% had only HIV-1 infection. The significant clinical features in HIV positive patients were chronic diarrhea (51.5%), prolonged fever (41.5%) and history of exposure (34%). Pulmonary tuberculosis could be diagnosed in 19.5% of HIV positive patients. In patients with prolonged/recurrent jaundice HBsAg and HIV was noted as a coinfection within 10/42 cases tested.
Increasing prevalence of HIV seropositivity was noted in patients admitted to an infectious disease hospital. Association of HIV infection with tuberculosis and in icteric cases with HBsAg was significant. The HIV screening should be carried out in patients with prolonged illness resistant to usual mode of treatment.
分析孟买一家传染病医院收治的HIV感染患者的临床病理特征。
对1996年9月1日至1998年2月28日收治的501例患者进行回顾性研究，这些患者因临床怀疑而接受HIV检测。通过微孔酶联免疫吸附试验对斑点试验结果进行双重确认来确定HIV血清阳性。
HIV血清阳性率为39.92%。其中94%为成年人，男性居多，96.5%仅感染HIV-1。HIV阳性患者的显著临床特征为慢性腹泻（51.5%）、长期发热（41.5%）和接触史（34%）。19.5%的HIV阳性患者可诊断为肺结核。在长期/反复黄疸的患者中，在检测的10/42例病例中发现HBsAg与HIV合并感染。
在一家传染病医院收治的患者中，HIV血清阳性率呈上升趋势。HIV感染与结核病以及黄疸病例中与HBsAg的关联显著。对于对常规治疗方式有抵抗力的长期患病患者，应进行HIV筛查。
