Schnorr D, Guddat H M, Neuser D, Correns H J, Dörner G, Mau S
Zentralbl Chir. 1979;104(7):436-45.
By well organized preventive examinations early tumour stages can be recognized. The diagnosis of prostatic cancer has to be secured by biopsy. The primary reliability of aspiration biopsies (cytology) was 94% compared with punch biopsies (histology) amounting to 73%. Indications and results of aspiration biopsies, radiological and nuclear medical techniques in diagnosing prostatic cancer are described. The combined anti-androgenic hormonal therapy (infusions of cytonal, subcapsular orchiectomy, permanent administration of oestrogen) is considered to be the unchanged basis of treatment. Comparative cytologic investigations in therapy indicate that high-voltage treatment connected with hormonal therapy seems to be superior to exclusive hormonal treatment. Observations after additional therapy by a radionuclid (89-Strontium) for affecting metastases are encouraging. Indications of a therapy by cytostatica in progressive prostatic cancer are explained.
通过精心组织的预防性检查，可以识别早期肿瘤阶段。前列腺癌的诊断必须通过活检来确定。穿刺活检（细胞学）的初步可靠性为94%，而打孔活检（组织学）为73%。文中描述了穿刺活检、放射学和核医学技术在诊断前列腺癌方面的适应症和结果。联合抗雄激素激素治疗（静脉输注赛托宁、包膜下睾丸切除术、长期服用雌激素）被认为是治疗的不变基础。治疗中的比较细胞学研究表明，与激素治疗相结合的高压治疗似乎优于单纯的激素治疗。用放射性核素（锶-89）进行辅助治疗以影响转移灶后的观察结果令人鼓舞。文中解释了在进展性前列腺癌中使用细胞抑制剂进行治疗的适应症。
