Janatpour K, Holland P
Sacramento Medical Foundation Blood Centers, 1625 Stockton Blvd, Sacramento, California 95816-7089, USA.
Indian J Pediatr. 2001 Feb;68(2):159-65. doi: 10.1007/BF02722038.
Increasingly complicated surgeries are being performed on neonatal and pediatric patients. Provision of a safe and adequate blood supply is essential for the success of many of these surgeries. Depending on the clinical situation, autologous and/or allogeneic blood may be used. However, in all cases, every attempt should be made to minimize the number of donor exposures to reduce the risk of transfusion transmitted infections. Transfusion of neonatal and pediatric patients requires additional considerations too, such as the risk of graft vs host disease, cytomegalovirus infection, the effects of various preservative anticoagulant solutions, electrolyte levels during blood storage, and wheather or not leukoreduced components are indicated.
越来越复杂的手术正在新生儿和儿科患者身上进行。为许多此类手术的成功提供安全充足的血液供应至关重要。根据临床情况,可使用自体血和/或异体血。然而,在所有情况下,都应尽一切努力减少供血者的接触次数,以降低输血传播感染的风险。新生儿和儿科患者的输血还需要额外考虑一些因素,例如移植物抗宿主病的风险、巨细胞病毒感染、各种保存抗凝溶液的影响、血液储存期间的电解质水平,以及是否需要白细胞滤除成分。