散发性新生儿脑裂畸形伴脑钙化

Sporadic neonatal schizencephaly associated with brain calcification.

作者信息

al-Alawi A M, al-Tawil K I, al-Hathal M M, Amir I

机构信息

Department of Pediatrics (Neonatology Division), King Fahad National Guard Hospital, Riyadh, Saudi Arabia.

出版信息

Ann Trop Paediatr. 2001 Mar;21(1):34-7; discussion 37-8.

PMID:11284244

Abstract

Schizencephaly rarely presents in the neonatal period. We present the case of a baby girl born with growth retardation and microcephaly who developed seizures on the 3rd day of life. There was no clinical or laboratory evidence of a congenital viral infection but brain imaging revealed widespread calcification and bilateral schizencephaly clefts. By the age of 11 months, she had developed gross psychomotor retardation.

摘要

脑裂畸形在新生儿期很少出现。我们报告一例出生时伴有生长发育迟缓及小头畸形的女婴，其在出生后第3天出现癫痫发作。没有先天性病毒感染的临床或实验室证据，但脑部影像学检查显示广泛钙化及双侧脑裂畸形裂隙。到11个月大时，她出现了严重的精神运动发育迟缓。