Jain S, Sodhani P, Gupta S, Sakhuja P, Kumar N
Department of Pathology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Acta Cytol. 2001 Mar-Apr;45(2):186-91. doi: 10.1159/000327275.
To review the cytomorphologic spectrum of the filarial worm and associated tissue response in 33 cases.
Retrospective analysis was carried out in clinically unsuspected cases of filariasis diagnosed on cytology over a period of 10 years. Twenty-nine aspirate smears from 28 patients were air dried and stained with May-Grünwald-Giemsa stain. Four routine cervical smears and one centrifuged smear of urine were stained with Papanicolaou stain.
Microfilariae alone and along with adult gravid females were present in 25 and 4 cases, respectively. In one case both adult male and female worms with microfilariae and eggs were seen. The diagnosis was based on the presence of eggs alone in one case and fragments of female worms in two. Four of these cases were neoplastic lesions, and microfilariae were found incidentally. In one case of splenomegaly microfilariae were seen along with Leishman-Donovan bodies.
Filariasis can be diagnosed on cytology by demonstrating microfilariae, a male or female worm, or eggs alone. It can be seen in association with neoplastic lesions and rarely with other parasitic infections.
回顾33例丝虫及其相关组织反应的细胞形态学谱。
对10年间经细胞学诊断的临床未怀疑的丝虫病病例进行回顾性分析。来自28例患者的29份抽吸涂片经空气干燥后用May-Grünwald-Giemsa染色。4份常规宫颈涂片和1份尿液离心涂片用巴氏染色法染色。
单独存在微丝蚴的有25例，同时存在微丝蚴和成年妊娠雌虫的有4例。1例同时见到成年雄虫和雌虫以及微丝蚴和虫卵。1例诊断仅基于虫卵的存在，2例基于雌虫碎片。其中4例为肿瘤性病变，微丝蚴为偶然发现。1例脾肿大病例中同时见到微丝蚴和利杜体。
通过发现微丝蚴、雄虫或雌虫或单独的虫卵，可在细胞学上诊断丝虫病。它可与肿瘤性病变相关，很少与其他寄生虫感染相关。
