Golomb B A, Vickrey B G, Hays R D
RAND Health Sciences Program and Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, USA.
Pharmacoeconomics. 2001;19(2):155-85. doi: 10.2165/00019053-200119020-00004.
The objective of this review was to evaluate health-related quality of life (HR-QOL) measures for use with patients with stroke. HR-QOL measures are increasingly used for assessment in many health conditions; these measures may serve an important role in evaluating the impact of stroke and of stroke interventions. HR-QOL measures used in patients with stroke should: (i) cover the domains of HR-QOL that may be affected by stroke; (ii) have administration characteristics suitable for use in patients with stroke; and (iii) have undergone reliability and validity assessment in patients with stroke. The present study evaluates HR-QOL measures with reference to these requirements. A systematic literature review was conducted to identify and evaluate HR-QOL measures of potential use in studies of patients with stroke. Identified measures were assessed with regard to stroke-relevant domains covered, measure characteristics (e.g. self-administration versus administration by an interviewer, interviewer time to complete) and psychometric properties of reliability and validity. The measures evaluated vary widely on domains covered, and limited assessment of the performance of HR-QOL measures has been conducted in patients with stroke. No existing measure comprehensively covers all relevant domains or addresses fully the issues of obtaining and combining HR-QOL assessments in patients and proxies in many stroke populations. Additional psychometric testing in stroke populations is needed for existing HR-QOL measures. In addition, stroke-targeted HR-QOL measures need to be developed and evaluated with patients with stroke.
本综述的目的是评估用于中风患者的健康相关生活质量（HR-QOL）测量方法。HR-QOL测量方法在许多健康状况评估中越来越常用；这些测量方法在评估中风及其干预措施的影响方面可能发挥重要作用。用于中风患者的HR-QOL测量方法应：（i）涵盖可能受中风影响的HR-QOL领域；（ii）具有适合中风患者使用的管理特性；（iii）在中风患者中进行过信度和效度评估。本研究参照这些要求对HR-QOL测量方法进行评估。进行了一项系统的文献综述，以识别和评估在中风患者研究中可能有用的HR-QOL测量方法。对识别出的测量方法在涵盖的与中风相关的领域、测量特性（例如自我管理与访谈者管理、访谈者完成时间）以及信度和效度的心理测量特性方面进行了评估。所评估的测量方法在涵盖的领域上差异很大，并且在中风患者中对HR-QOL测量方法性能的评估有限。没有现有的测量方法能全面涵盖所有相关领域，也没有完全解决在许多中风人群中获取和综合患者及代理人的HR-QOL评估的问题。现有的HR-QOL测量方法需要在中风人群中进行额外的心理测量测试。此外，需要针对中风患者开发并评估以中风为目标的HR-QOL测量方法。
