• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Helicobacter pylori genetic diversity and risk of human disease.

作者信息

Blaser M J, Berg D E

机构信息

Department of Medicine, New York University, School of Medicine and Veterans Affairs Medical Center, New York, New York 10016, USA.

出版信息

J Clin Invest. 2001 Apr;107(7):767-73. doi: 10.1172/JCI12672.

DOI:10.1172/JCI12672
PMID:11285290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC199587/
Abstract
摘要

相似文献

1
Helicobacter pylori genetic diversity and risk of human disease.幽门螺杆菌的遗传多样性与人类疾病风险
J Clin Invest. 2001 Apr;107(7):767-73. doi: 10.1172/JCI12672.
2
Helicobacter pylori vacA d1 genotype is associated with gastric cancer but not peptic ulcers in Kurdistan region, northern Iraq.
Asian Pac J Cancer Prev. 2014;15(14):5965-6. doi: 10.7314/apjcp.2014.15.14.5965.
3
The role of the putative virulence markers (cagA and vacA ) of Helicobacter pylori in peptic ulcer disease.幽门螺杆菌假定毒力标志物(cagA和vacA)在消化性溃疡疾病中的作用。
Saudi Med J. 2004 Jul;25(7):830-6.
4
[Organization of the Helicobacter pylori genome].[幽门螺杆菌基因组的组织]
Postepy Hig Med Dosw. 2001;55(3):355-67.
5
The EPIYA-ABCC motif pattern in CagA of Helicobacter pylori is associated with peptic ulcer and gastric cancer in Mexican population.幽门螺杆菌CagA中的EPIYA-ABCC基序模式与墨西哥人群的消化性溃疡和胃癌有关。
BMC Gastroenterol. 2014 Dec 24;14:223. doi: 10.1186/s12876-014-0223-9.
6
Multiple gene status in Helicobacter pylori strains and risk of gastric cancer development.幽门螺杆菌菌株的多种基因状态与胃癌发展风险。
Digestion. 2009;80(3):200-7. doi: 10.1159/000229774. Epub 2009 Sep 15.
7
Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms.幽门螺杆菌cagA和vacA基因多态性的临床相关性
Gastroenterology. 2008 Jul;135(1):91-9. doi: 10.1053/j.gastro.2008.03.041. Epub 2008 Mar 25.
8
Association of Helicobacter pylori cagA Gene with Gastric Cancer and Peptic Ulcer in Saudi Patients.沙特患者中幽门螺杆菌cagA基因与胃癌及消化性溃疡的关联
J Microbiol Biotechnol. 2015 Jul;25(7):1146-53. doi: 10.4014/jmb.1501.01099.
9
[Genomic structure of Helicobacter pylori and its pathogenecity].[幽门螺杆菌的基因组结构及其致病性]
Nihon Saikingaku Zasshi. 2000;55(4):629-48.
10
Lack of correlation of vacA genotype, cagA gene of Helicobacter pylori and their expression products with various gastroduodenal diseases.幽门螺杆菌vacA基因型、cagA基因及其表达产物与各种胃十二指肠疾病之间缺乏相关性。
Chin Med J (Engl). 2001 Jul;114(7):703-6.

引用本文的文献

1
IRON DEFICIENCY PROMOTES -INDUCED GASTRIC CARCINOGENESIS BY ENABLING RECIPROCITY BETWEEN CARCINOGENIC SECONDARY BILE ACIDS AND PROTECTIVE LONG-CHAIN FATTY ACIDS.缺铁通过促使致癌性次级胆汁酸与保护性长链脂肪酸之间产生相互作用,从而促进幽门螺杆菌诱导的胃癌发生。
Trans Am Clin Climatol Assoc. 2025;135:206-221.
2
Biochemical and structural characterization of a GNAT superfamily protein acetyltransferase from Helicobacter pylori.幽门螺杆菌GNAT超家族蛋白乙酰转移酶的生化与结构特征
J Biol Chem. 2025 Jun 10;301(7):110356. doi: 10.1016/j.jbc.2025.110356.
3
induced miR-362-5p upregulation drives gastric cancer progression and links hepatocellular carcinoma through an exosome-dependent pathway.诱导的miR-362-5p上调通过外泌体依赖途径驱动胃癌进展并与肝细胞癌相关联。
Front Cell Infect Microbiol. 2025 May 8;15:1582131. doi: 10.3389/fcimb.2025.1582131. eCollection 2025.
4
Long-term assessment of Helicobacter pylori cagA EPIYA motif changes and pathology outcomes in gastric biopsies of dyspeptic patients: 10-year follow-up.消化不良患者胃活检中幽门螺杆菌cagA EPIYA基序变化及病理结果的长期评估:10年随访
BMC Gastroenterol. 2024 Dec 19;24(1):466. doi: 10.1186/s12876-024-03516-0.
5
Molecular insights into the fine-tuning of pH-dependent ArsR-mediated regulation of the SabA adhesin in Helicobacter pylori.深入了解 pH 依赖性 ArsR 介导的幽门螺杆菌 SabA 黏附素调节的分子机制。
Nucleic Acids Res. 2024 Jun 10;52(10):5572-5595. doi: 10.1093/nar/gkae188.
6
Targeting hypoxia-inducible factor-1 alpha suppresses -induced gastric injury via attenuation of both -mediated microbial virulence and proinflammatory host responses.靶向缺氧诱导因子-1α通过抑制毒力和促炎宿主反应抑制诱导的胃损伤。
Gut Microbes. 2023 Dec;15(2):2263936. doi: 10.1080/19490976.2023.2263936. Epub 2023 Oct 13.
7
High-Salt Diet Exacerbates Infection and Increases Gastric Cancer Risks.高盐饮食会加剧感染并增加患胃癌风险。
J Pers Med. 2023 Aug 28;13(9):1325. doi: 10.3390/jpm13091325.
8
High prevalence of mixed infections identified by multilocus sequence typing in Ningbo, China.中国宁波通过多位点序列分型鉴定出的混合感染高流行率。
Front Microbiol. 2023 Aug 8;14:1207878. doi: 10.3389/fmicb.2023.1207878. eCollection 2023.
9
Divide and conquer: genetics, mechanism, and evolution of the ferrous iron transporter Feo in .分而治之:[具体物种]中铁转运蛋白Feo的遗传学、机制及进化
Front Microbiol. 2023 Jul 4;14:1219359. doi: 10.3389/fmicb.2023.1219359. eCollection 2023.
10
Helicobacter pylori-activated fibroblasts as a silent partner in gastric cancer development.幽门螺杆菌激活的成纤维细胞作为胃癌发展中的沉默伙伴。
Cancer Metastasis Rev. 2023 Dec;42(4):1219-1256. doi: 10.1007/s10555-023-10122-1. Epub 2023 Jul 17.

本文引用的文献

1
The simple sequence contingency loci of Haemophilus influenzae and Neisseria meningitidis.流感嗜血杆菌和脑膜炎奈瑟菌的简单序列可变位点
J Clin Invest. 2001 Mar;107(6):657-62. doi: 10.1172/JCI12557.
2
Inverse relationship between gastric colonization of Helicobacter pylori and diarrheal illnesses in children: results of a population-based cross-sectional study.儿童幽门螺杆菌胃定植与腹泻性疾病之间的负相关关系:一项基于人群的横断面研究结果
J Infect Dis. 2000 Nov;182(5):1446-9. doi: 10.1086/315887. Epub 2000 Oct 3.
3
Identification of type II restriction and modification systems in Helicobacter pylori reveals their substantial diversity among strains.幽门螺杆菌中II型限制与修饰系统的鉴定揭示了它们在菌株间的显著多样性。
Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9671-6. doi: 10.1073/pnas.97.17.9671.
4
Lewis antigens in Helicobacter pylori: biosynthesis and phase variation.幽门螺杆菌中的Lewis抗原:生物合成与相变
Mol Microbiol. 2000 Jun;36(6):1187-96. doi: 10.1046/j.1365-2958.2000.01934.x.
5
Differences in genotypes of Helicobacter pylori from different human populations.不同人群中幽门螺杆菌基因型的差异。
J Bacteriol. 2000 Jun;182(11):3210-8. doi: 10.1128/JB.182.11.3210-3218.2000.
6
Interleukin-1 polymorphisms associated with increased risk of gastric cancer.与胃癌风险增加相关的白细胞介素-1基因多态性。
Nature. 2000 Mar 23;404(6776):398-402. doi: 10.1038/35006081.
7
Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion.幽门螺杆菌细胞毒素相关基因A(CagA)通过IV型分泌系统转移至胃上皮细胞。
Science. 2000 Feb 25;287(5457):1497-500. doi: 10.1126/science.287.5457.1497.
8
Modulation of Helicobacter pylori induced interleukin-8 synthesis in gastric epithelial cells mediated by cag PAI encoded VirD4 homologue.由cag致病岛编码的VirD4同源物介导的幽门螺杆菌诱导胃上皮细胞白细胞介素-8合成的调节
J Clin Pathol. 1999 Sep;52(9):653-7. doi: 10.1136/jcp.52.9.653.
9
Quasispecies development of Helicobacter pylori observed in paired isolates obtained years apart from the same host.在相隔数年从同一宿主获得的配对分离株中观察到的幽门螺杆菌准种演变。
J Infect Dis. 2000 Jan;181(1):273-82. doi: 10.1086/315173.
10
Shaping the genome--restriction-modification systems as mobile genetic elements.塑造基因组——作为可移动遗传元件的限制修饰系统
Curr Opin Genet Dev. 1999 Dec;9(6):649-56. doi: 10.1016/s0959-437x(99)00026-x.