Bioavailability of nutrients: a practical approach to in vitro demonstration of the availability of nutrients in multivitamin-mineral combination products.

As the dietary supplements industry is registering steady and rapid growth, consumers are demanding quality supplements. Consumer perception of the quality of oral solid dosage forms is changing. Good quality is associated with the ability to disintegrate and dissolve. Performance characteristics of oral solid dosage forms in public standards will address the in vitro dissolution requirements, which will be presented as they relate to multivitamin-mineral combination products.