Okubo M, Nykanen D, Benson L N
Department of Pediatrics, Division of Cardiology, Variety Club Catheterization Laboratories, Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.
Catheter Cardiovasc Interv. 2001 Apr;52(4):510-7. doi: 10.1002/ccd.1114.
Thirteen children (seven male) with coronary artery fistula underwent percutaneous transcatheter occlusion. The age range was 8 months to 14 years (mean, 6.3 years). The fistulas had their origins from the right coronary artery (six), from the left anterior descending coronary artery (three), and from the left circumflex coronary artery (four). Drainage was to the right ventricle (seven), the right atrium (three), and one each to the pulmonary artery, left atrium, and superior caval vein. The fistulas were closed with coils in 10 patients, a Rashkind double-umbrella device in 1 patient, and an Amplatzer Duct Occluder in 2 patients. Complete occlusion was achieved in 9 of 13 patients. Complications consisted of migration of coils in four and transient arrhythmias or changes in the resting electrocardiogram in four patients. Follow-up studies 1 to 31 months (mean, 14.6 months) after occlusion noted only four patients with trivial (clinically insignificant) residual shunts. Owing to various coronary fistula morphologies, transcatheter occlusion requires availability of different embolization techniques. Short-term follow-up supports persistent clinical efficacy and transcatheter closure techniques as the initial form of therapy.
13例冠状动脉瘘患儿(7例男性)接受了经皮导管封堵术。年龄范围为8个月至14岁(平均6.3岁)。瘘管起源于右冠状动脉(6例)、左冠状动脉前降支(3例)和左冠状动脉回旋支(4例)。引流至右心室(7例)、右心房(3例),分别有1例引流至肺动脉、左心房和上腔静脉。10例患者用弹簧圈封堵瘘管,1例用Rashkind双伞装置封堵,2例用Amplatzer动脉导管封堵器封堵。13例患者中有9例实现完全封堵。并发症包括4例弹簧圈移位,4例患者出现短暂性心律失常或静息心电图改变。封堵术后1至31个月(平均14.6个月)的随访研究发现,只有4例患者存在轻微(临床无意义)残余分流。由于冠状动脉瘘形态各异,经皮导管封堵需要采用不同的栓塞技术。短期随访支持经皮导管封堵术作为初始治疗形式具有持续的临床疗效。