Mosimann F, Bettschart V, Gardaz J P, Fontolliet C, Tissot J D, Meuwly J Y, Chioléro R, Gillet M
Service de chirurgie, CHUV.
Rev Med Suisse Romande. 2001 Feb;121(2):95-9.
From 1988 to June 2000 138 transplantations were performed in 129 adult patients. Actuarial patient and graft survivals have been 80.7% and 75.4% at one year and 67.8% and 63.5% at 10 years. This compares favourably with the statistics of the European Liver Transplant Registry that collected data from more than 30,000 grafts. Over the twelve years of activity, the indications have become more liberal and the techniques have been simplified. The waiting list has therefore grown and some patients are now unfortunately dying before a graft can be found because the number of brain dead donors remains stable. In order to palliate this shortage, older donors are now being accepted even with co-morbidities and/or moderate alterations of the liver function tests. The use of live donors and the split of the best cadaveric grafts for two recipients will also reduce the gap between the demand and the offer.
1988年至2000年6月，对129例成年患者实施了138例肝移植手术。患者和移植物的精算生存率在1年时分别为80.7%和75.4%，在10年时分别为67.8%和63.5%。与收集了30000多例移植物数据的欧洲肝移植登记处的统计数据相比，这一结果较为理想。在12年的活动中，肝移植的适应证更加宽松，技术也得到了简化。因此，等待肝移植的名单有所增加，现在一些患者不幸在找到供体之前就死亡了，因为脑死亡供体的数量保持稳定。为了缓解这种短缺状况，现在即使是有合并症和/或肝功能检查有中度异常的老年供体也被接受。使用活体供体以及将最佳尸体移植物分给两位受者也将缩小供需之间的差距。
