Hohn B, Levy A A, Puchta H
Friedrich Miescher Institute, Maulbeerstrasse 66, 4058 Basel, Switzerland.
Curr Opin Biotechnol. 2001 Apr;12(2):139-43. doi: 10.1016/s0958-1669(00)00188-9.
Selection markers, which were necessary for the isolation of transgenic plants, are no longer required in mature plants, especially when they are grown in fields. Regimes to achieve their efficient elimination, mostly through site-specific recombination or transposition, are being developed.
用于分离转基因植物的选择标记在成熟植物中不再需要,尤其是当它们在田间种植时。目前正在开发主要通过位点特异性重组或转座来实现其有效消除的方法。