Li W X, Ding S W
Department of Plant Pathology, University of California, Riverside, CA 92521, USA.
Curr Opin Biotechnol. 2001 Apr;12(2):150-4. doi: 10.1016/s0958-1669(00)00190-7.
The suppression of RNA silencing by plant viruses represents a viral adaptation to a novel host antiviral defense. Three types of viral suppressors have been identified through the use of a variety of silencing suppression assays. The first two types of suppressor are capable of a complete or partial reversal of pre-existing RNA silencing; the third type does not reverse RNA silencing but can instead prevent its systemic signaling.
植物病毒对RNA沉默的抑制代表了病毒对宿主新型抗病毒防御机制的一种适应。通过使用多种沉默抑制试验,已鉴定出三种类型的病毒抑制子。前两种类型的抑制子能够完全或部分逆转已存在的RNA沉默;第三种类型不会逆转RNA沉默,但可以阻止其系统性信号传导。