Sandhu S K, King T D, Troutman W B, Hixon R L, Kiel E A, Bourgeois K V
Pediatric Cardiology, Children's Hospital and Louisiana State University Health Sciences Center, 200 Henry Clay Avenue, New Orleans, LA 70118, USA.
J Invasive Cardiol. 2001 Apr;13(4):298-302.
Transcatheter closure of the patent ductus arteriosus is a well established procedure. The objective of this study was to assess the effectiveness and the safety of the Amplatzer duct occluder.
Occlusion of the patent ductus arteriosus was attempted in 23 patients. The median weight was 11.7 Kg (range, 5 kg - 42.4 kg) with a mean ductus diameter of 3.7 mm (range, 1.6 - 7.2 mm). The immediate closure rate was 86% with a closure rate of 100% at 6 months, 1 year and 2 years following device placement. There was one device embolization that occurred immediately following device placement. No patient had aortic narrowing or pulmonary artery stenosis following the procedure.
The Amplatzer duct occluder is safe and effective in the closure of a patent ductus arteriosus up to 7.2 mm in diameter. Selecting a device at least 12 mm larger than the minimal ductal diameter can minimize embolization.
经导管动脉导管未闭封堵术是一种成熟的手术。本研究的目的是评估Amplatzer动脉导管封堵器的有效性和安全性。
对23例患者尝试进行动脉导管未闭封堵术。患者体重中位数为11.7千克(范围5千克至42.4千克),动脉导管平均直径为3.7毫米(范围1.6至7.2毫米)。即刻封堵成功率为86%,在装置置入后6个月、1年和2年时封堵成功率为100%。有1例装置在置入后即刻发生栓塞。术后无患者出现主动脉缩窄或肺动脉狭窄。
Amplatzer动脉导管封堵器在封堵直径达7.2毫米的动脉导管未闭时安全有效。选择比最小导管直径至少大12毫米的装置可将栓塞风险降至最低。