Kvist T
Department of Endodontology/Oral Diagnosis, Faculty of Odontology, Göteborg University, Sweden.
Swed Dent J Suppl. 2001(144):1-57.
Epidemiological surveys have reported that 25%-35% of root filled teeth are associated with periapical radiolucencies. Descriptive studies have demonstrated that clinicians' decision making regarding such teeth are subject to substantial variation. A coherent model to explain the observed variation has not been produced. In the present thesis a "Praxis Concept theory" was proposed. The theory suggests that dentists perceive periapical lesions of varying sizes as different stages on a continuous health scale. Interindividual variations can then be regarded as the result of the choice of different cut-off points on the continuum for prescribing retreatment. In the present study experiments among novice and expert decision makers gave evidence in favour of the theory. Data also suggested that the choice of retreatment criterion is affected by values, costs of retreatment and technical quality of original treatment. From a prescriptive point of view, the presence of a persistent periapical radiolucency has often been used as a criterion of endodontic "failure" and as an indication for endodontic retreatment. As an alternative decision strategy, the use of decision analysis has been proposed. Logical display of decision alternatives, values of probabilities, utility values (U-values) of the different outcomes and calculation of optimal decision strategy are features of this theory. The implementation of this approach is impeded by the uncertainty of outcome probabilities and lack of investigations concerning U-values. U-values of two periapical health states in root filled teeth (with and without a periapical lesion respectively) were investigated in a group of 82 dental students and among 16 Swedish endodontists. Two methods were used to elicit U-values: Standard gamble and Visual Analogue Scale. Large interindividual variation for both health states were recorded. The difference in U-values between the two health states was found to be statistically significant regardless of assessment method. Compared with Standard gamble Visual Analogue Scale systematically produced lower ratings. U-values were found to change considerably in both the short and long-term. Any significant correlation between endodontists' U-values and retreatment prescriptions could not be demonstrated. Surgical and nonsurgical retreatment were randomly assigned to 95 "failed" root filled teeth in 92 patients. Cases were followed clinically and radiographically for four years postoperatively. At the 12-month recall a statistically significant higher healing rate was observed for teeth retreated surgically. At the final 48-month recall no systematic difference was detected. Patients were found to be more subject to postoperative discomfort when teeth were retreated surgically compared with nonsurgically. Consequently, surgical retreatment tended to be associated with higher indirect costs than a nonsurgically approach. In the final part of the thesis it is argued that retreatment decision making in everyday clinical practice normally should be based on simple principles. It is suggested that in order to achieve the best overall consequence a periapical lesion in a root filled tooth that is not expected to heal should be retreated. Arguments to withhold retreatment should be based on (i) respect for patient autonomy, (ii) retreatment risks or (iii) retreatment costs.
流行病学调查显示,25% - 35%的根管充填牙伴有根尖周透射区。描述性研究表明,临床医生对于此类牙齿的决策存在很大差异。尚未形成一个连贯的模型来解释所观察到的差异。在本论文中,提出了一种“实践概念理论”。该理论认为,牙医将不同大小的根尖周病变视为连续健康尺度上的不同阶段。个体间的差异可被视为在连续体上选择不同的截断点以规定再治疗的结果。在本研究中,新手和专家决策者的实验为该理论提供了支持证据。数据还表明,再治疗标准的选择受价值观、再治疗成本和初始治疗技术质量的影响。从规范性角度来看,持续存在的根尖周透射区常被用作牙髓“失败”的标准以及牙髓再治疗的指征。作为一种替代决策策略,有人提出使用决策分析。决策备选方案的逻辑展示、概率值、不同结果的效用值(U值)以及最优决策策略的计算是该理论的特点。这种方法的实施受到结果概率的不确定性以及缺乏关于U值的研究的阻碍。在一组82名牙科学生和16名瑞典牙髓病医生中,对根管充填牙的两种根尖周健康状态(分别为有和没有根尖周病变)的U值进行了研究。使用了两种方法来获取U值:标准博弈法和视觉模拟量表法。记录到两种健康状态下个体间均存在较大差异。无论采用何种评估方法,两种健康状态下的U值差异均具有统计学意义。与标准博弈法相比,视觉模拟量表法得出的评分系统性地更低。发现U值在短期和长期内都有相当大的变化。未发现牙髓病医生的U值与再治疗处方之间存在任何显著相关性。对92例患者的95颗“失败”根管充填牙随机分配进行手术再治疗和非手术再治疗。术后对病例进行了四年的临床和影像学随访。在12个月的复查时,观察到手术再治疗的牙齿愈合率在统计学上显著更高。在最后的48个月复查时,未检测到系统性差异。发现与非手术再治疗相比,手术再治疗的患者术后不适更明显。因此,手术再治疗往往比非手术方法产生更高的间接成本。在论文的最后部分,有人认为日常临床实践中的再治疗决策通常应基于简单原则。建议为了实现最佳的总体结果,对于预计不会愈合的根管充填牙中的根尖周病变应进行再治疗。不进行再治疗的理由应基于(i)尊重患者自主权,(ii)再治疗风险或(iii)再治疗成本。