肥皂和表面活性剂引起的角膜麻醉，在兔和人类中的相关性缺乏。

Corneal anesthesia induced by soaps and surfactants, lack of correlation in rabbits and humans.

作者信息

Harris L S, Kahanowicz Y, Shimmyo M

出版信息

Ophthalmologica. 1975;170(4):320-5. doi: 10.1159/000307228.

Abstract

Five commonly marketed bath and facial soaps and four commercially available hair shampoos were studied for their anesthetic effect on human and rabbit corneas. These compounds all produced anesthesia comparable to that induced by tetracaine hydrochloride 0.5 percent but lasting several hours longer in rabbits. None of the soaps or shampoos produced corneal anesthesia in humans. Studies of corneal anesthesia in rabbits may not be extrapolated to the human eye.

摘要

对五种常见的市售沐浴皂和洁面皂以及四种市售洗发水进行了研究，以考察它们对人及兔角膜的麻醉作用。这些化合物产生的麻醉效果与0.5%盐酸丁卡因相当，但在兔身上持续时间长数小时。这些肥皂和洗发水均未在人体产生角膜麻醉作用。对兔角膜麻醉的研究结果不能外推至人眼。