Wang F I, Ting C T, Liu Y S
Department of Veterinary Medicine, National Taiwan University, Taipei.
J Vet Diagn Invest. 2001 Mar;13(2):159-61. doi: 10.1177/104063870101300211.
A 13-year-old intact female mixed-breed dog was presented for a progressive enlargement of the right eye, which had been treated previously for conjunctivitis. A round, firm mass, approximately 4 cm in diameter, was protruding from the superotemporal aspect of the right orbit, displacing the eyeball anteriorly and ventromedially. The mass was encapsulated, distinct from the eyeball, and not associated with the eyelids. On cut surface, there was a pale multilobulated periphery, with a dark red, soft, and depressed core. Histologically, tumor cells formed cords and tubules, which were stained with mouse anti-human cytokeratin antibody AE1/AE3. Residual glands were serous, and the majority of tumor cells were negative for mucin. The supraorbital location, encapsulation, and residual serous glands suggest that this mass was a low-grade adenocarcinoma of the lacrimal gland.
一只13岁未绝育的雌性混种犬因右眼渐进性肿大前来就诊，该犬右眼此前曾患结膜炎。一个直径约4厘米的圆形、质地坚硬的肿块从右眼眶颞上侧突出，将眼球向前和腹内侧推移。肿块有包膜，与眼球分离，与眼睑无关。在切面上，周边呈淡色多叶状，中央为暗红色、质地柔软且凹陷。组织学检查显示，肿瘤细胞形成条索和小管，用小鼠抗人细胞角蛋白抗体AE1/AE3染色。残留腺体为浆液性，大多数肿瘤细胞黏液染色阴性。眶上部位、包膜及残留浆液性腺提示该肿块为泪腺低度腺癌。
