Genetic factors in susceptibility of Biomphalaria glabrata for different strains of Schistosoma mansoni.

Biomphalaria glabrata selected for genetic differences in susceptibility to infection with a Puerto Rican strain of Schistosoma mansoni were exposed to miracidia of a strain of S. mansoni from St Lucia. The St Lucian strain was less infective than the Puerto Rican. Results suggested that in snails susceptible to the Puerto Rican S. mansoni differences in susceptibility to the St Lucian straing were determined by a single gene, with insusceptibility dominant.