Wakaumi M, Shiga T, Nozaki K, Fujiu K, Shimaya K, Ishizuka N, Matsuda N, Kasanuki H
Department of Cardiology, The Heart Institute of Japan, Tokyo Women's Medical University, Japan.
Heart Vessels. 2000;15(3):144-6. doi: 10.1007/pl00007266.
Continuous intravenous infusion of prostacyclin (epoprostenol) as a treatment for primary pulmonary hypertension (PPH) definitely improves the patient's quality of life, but few accurate parameters have been found to evaluate the efficacy of the treatment. We observed a patient with severe PPH whose plasma brain natriuretic peptide (BNP) level changed significantly as her condition and symptoms changed. Plasma BNP may be considered as one of the parameters for assessing the efficacy of prostacyclin treatment.
持续静脉输注前列环素（依前列醇）作为原发性肺动脉高压（PPH）的一种治疗方法确实能改善患者的生活质量，但尚未发现有多少准确的参数可用于评估该治疗的疗效。我们观察了一名重度PPH患者，其血浆脑钠肽（BNP）水平随病情和症状的变化而显著改变。血浆BNP可被视为评估前列环素治疗疗效的参数之一。
