Harari A, Nitenberg G, Rapin M, Samii K, Lemaire F, Le Gall J R
Nouv Presse Med. 1975 Jan 18;4(3):153-7.
Twenty cases of hypovolemic shock of various etiologies in which initial diagnosis was massive pulmonary embolism are analyzed. The error was due to intensity of respiratory failure symptoms and electrocardiographic changes suggesting acute cor pulmonale. However, although constant, hypoxemia was mild and easily corrected by oxygen administration. Hypovolemia was confirmed by low central venous pressure (CPV EQUALS 1, 3 cm H20); in 7 patients, right heart catheterism showed lowered cardiac output associated to low ventricular filling pressures (VFP). Rapid blood volume expansion simultaneously corrected in all cases both shock and clinical signs of "respiratory failure", while CVP increased only slightly. These findings suggest that CVP must be carefully checked when faced with a clinical picture of massive pulmonary embolism and if low, rapid blood volume expansion must be performed under CVP monitoring, in order to rule out hypovolemic shock.
分析了20例病因各异的低血容量性休克病例,这些病例最初被诊断为大面积肺栓塞。误诊是由于呼吸衰竭症状的严重程度以及提示急性肺心病的心电图变化。然而,尽管低氧血症持续存在,但程度较轻,通过吸氧很容易纠正。中心静脉压降低(CPV等于1、3cmH₂O)证实存在低血容量;7例患者经右心导管检查显示心输出量降低,同时心室充盈压(VFP)也降低。所有病例通过快速扩充血容量同时纠正了休克和“呼吸衰竭”的临床体征,而中心静脉压仅略有升高。这些发现表明,面对大面积肺栓塞的临床表现时,必须仔细检查中心静脉压,如果中心静脉压较低,必须在中心静脉压监测下进行快速扩充血容量,以排除低血容量性休克。