Bhangoo R K
Pediatric and Developmental Neuropsychiatry Branch, National Institute of Mental Health, 10 Center Drive, Building 10 Room 4N-208, Bethesda, MD 20892, USA.
Semin Clin Neuropsychiatry. 2000 Oct;5(4):250-8. doi: 10.1053/scnp.2000.16529.
Advances in neurobiological research suggest that certain frontal-subcortical circuits play important roles in idiopathic obsessive-compulsive disorder and Tourette's syndrome. Tics and obsessive-compulsive behaviors secondary to neurologic insult appear to involve the same neural circuitry. There are few systematic studies of the treatment of obsessive-compulsive behaviors and tics associated with neurologic disorders. However knowledge of the circuitry and associated neurochemistry of these disorders can help to outline a rational approach to these behaviors.
神经生物学研究的进展表明，某些额叶-皮质下环路在特发性强迫症和妥瑞氏综合征中起重要作用。继发于神经损伤的抽动和强迫行为似乎涉及相同的神经回路。关于与神经系统疾病相关的强迫行为和抽动的治疗，系统研究很少。然而，了解这些疾病的神经回路和相关神经化学有助于勾勒出针对这些行为的合理治疗方法。
