Savchenko O N, Strel'tsova N A
Probl Endokrinol (Mosk). 1975 Mar-Apr;21(2):38-41.
A study was made of 151 healthy pregnant women at periods of from 4 to 41 weeks of pregnancy. There was revealed no correlation between the level of excretion of the CG and estriol, and also of the CG and pregnandiol from the 7th to the 41st weeks of pregnancy; consequently CG played no role in the regulation of steroidogenesis in the placenta. Between the levels of CH and progesterone in the blood there existed a significant positive association from the 4th to the 7th week of pregnancy; this correlation disappeared from the 8th week. Consequently, the CG retained its steroidogenic action on the corpus luteum of pregnancy. The activity of the corpus luteum in respect to progesterone production decreased considerably as soon as the 7th week of pregnancy.
对151名怀孕4至41周的健康孕妇进行了一项研究。结果显示，从怀孕第7周到第41周，人绒毛膜促性腺激素（CG）与雌三醇的排泄水平之间，以及CG与孕二醇的排泄水平之间均无相关性；因此，CG在胎盘类固醇生成的调节中不起作用。在怀孕第4周到第7周，血液中CG水平与孕酮水平之间存在显著的正相关；从第8周起这种相关性消失。因此，CG对妊娠黄体保留其类固醇生成作用。妊娠黄体产生孕酮的活性在怀孕第7周时就大幅下降。
