Attum A A, Hankins J R, Ngangana J, McLaughlin J S
Ann Thorac Surg. 1979 Aug;28(2):126-32. doi: 10.1016/s0003-4975(10)63768-x.
Segments ranging from 40 to 70% of the thoracic esophagus were resected in 80 mongrel dogs. End-to-end anastomosis was effected after circular myotomy either proximal or distal, or both proximal and distal, to the anastomosis. Among dogs undergoing resection of 60% of the esophagus, distal myotomy enabled 6 of 8 animals to survive, and combined proximal and distal myotomy permitted 8 of 10 to survive. Cineesophagography was performed in a majority of the 50 surviving animals and showed no appreciable delay of peristalsis at the myotomy sites. When these sites were examined at postmortem examination up to 13 months after operation, 1 dog showed a small diverticulum but none showed dilatation or stricture. It is concluded that circular myotomy holds real promise as a means of extending the clinical application of esophageal resection with end-to-end anastomosis.
在80只杂种犬中切除了胸段食管40%至70%的节段。在吻合口近端或远端,或近端和远端同时进行环形肌切开术后进行端端吻合。在接受60%食管切除术的犬中,远端肌切开术使8只动物中的6只存活,近端和远端联合肌切开术使10只中的8只存活。在50只存活动物中的大多数进行了食管造影,结果显示在肌切开术部位蠕动没有明显延迟。当在术后长达13个月的尸检中检查这些部位时,1只犬出现了一个小憩室,但没有一只出现扩张或狭窄。结论是,环形肌切开术作为一种扩大食管端端吻合切除术临床应用的方法具有切实的前景。