Dietz H P, Clarke B
Royal Women's Hospital, Brisbane, Australia.
Int Urogynecol J Pelvic Floor Dysfunct. 2001;12(1):38-41. doi: 10.1007/s001920170092.
In a prospective study 105 patients with symptoms of stress incontinence underwent video-urodynamic testing, including resting urethral pressure profilometry and translabial ultrasound. The urethral pressure profile (UPP) included maximum urethral closure pressure (MUCP), functional length (FL) and area under the curve (AUC). Ultrasound parameters included urethral thickness, urethral rotation and bladder neck descent, as well as funneling/opening of the internal urethral meatus on Valsalva maneuver. Levator contraction strength was assessed measuring the cranioventral displacement of the internal meatus. Negative correlations between UPP data and age, parity and previous surgery were observed which were consistent with literature data. There was a positive correlation between the urethral AP diameter on ultrasound and the MUCP, which agrees with reports showing reduced sphincter thickness or volume in stress-incontinent women. Hypermobility on ultrasound did not correlate with UPP data. However, a lower MUCP correlated with extensive opening of the bladder neck. Finally, there was a trend towards poorer pelvic floor function with lower MUCP measurements.
在一项前瞻性研究中，105例有压力性尿失禁症状的患者接受了影像尿动力学检查，包括静息尿道压力测定和经阴唇超声检查。尿道压力曲线（UPP）包括最大尿道闭合压（MUCP）、功能长度（FL）和曲线下面积（AUC）。超声参数包括尿道厚度、尿道旋转和膀胱颈下移，以及瓦尔萨尔瓦动作时尿道内口的漏斗状/开放情况。通过测量尿道内口的颅腹侧移位来评估提肌收缩强度。观察到UPP数据与年龄、产次和既往手术之间存在负相关，这与文献数据一致。超声测量的尿道前后径与MUCP之间存在正相关，这与关于压力性尿失禁女性括约肌厚度或体积减小的报道相符。超声检查显示的尿道活动过度与UPP数据无关。然而，较低的MUCP与膀胱颈的广泛开放相关。最后，MUCP测量值较低时，盆底功能有变差的趋势。
