Contribution of new techniques for the diagnosis of congenital toxoplasmosis.

Congenital toxoplasmosis is still a concern, particularly in France, where the seroprevalence is high. For an efficient prevention program, reliable techniques are necessary. During the past ten years, biological advances have been made to improve the performance of antenatal diagnosis as well as the postnatal detection of infected neonates. In this review we will touch on three main points: 1) the dating of seroconversion during the course of pregnancy, 2) the value of antenatal diagnosis, 3) the new modalities for postnatal serological follow-up of newborns.