Gates G F, Dore E K
Radiology. 1975 Jun;115(3):665-71. doi: 10.1148/15.3.665.
Growth patterns of the cranial sutures were studied by bone scanning in 29 children, 13 of whom had craniosynostosis. Primary craniosynostosis was initiated by localized bony fusion across a suture, associated with an abnormal accumulation of bone-seeking radiopharmaceuticals. As the abnormal fusion process extended along the suture, there was a corresponding spread of radionuclide. With complete fusion, uptake diminished. In addition to calvarial scanning, three abnormal sutures were scanned following surgical excision, which allowed direct comparison in vivo and in vitro. Calvarial bone scanning is helpful in the early detection of primary craniosynostosis.
通过骨扫描研究了29名儿童颅骨缝的生长模式，其中13名患有颅缝早闭。原发性颅缝早闭由缝线处局部骨融合引发，伴有亲骨性放射性药物异常聚集。随着异常融合过程沿缝线延伸，放射性核素相应扩散。完全融合时，摄取减少。除了颅骨扫描外，对3条异常缝线在手术切除后进行了扫描，这使得能够在体内和体外进行直接比较。颅骨骨扫描有助于原发性颅缝早闭的早期检测。
