胶质瘤细胞系中通过低密度脂蛋白受体对卟啉和低密度脂蛋白的竞争性摄取：流式细胞术分析
Competitive uptake of porphyrin and LDL via the LDL receptor in glioma cell lines: flow cytometric analysis.
作者信息
Shibata Y, Matsumura A, Yoshida F, Yamamoto T, Nakai K, Nose T, Sakata I, Nakajima S
机构信息
Department of Neurosurgery, University of Tsukuba, Tsukuba, 305-8575, Ibaraki, Japan.
出版信息
Cancer Lett. 2001 May 10;166(1):79-87. doi: 10.1016/s0304-3835(00)00717-5.
Abstract
We examined the simultaneous uptake of porphyrin and (LDL) by four established cell lines of glioma and normal fibroblasts using flow cytometry (FCM). The results indicated porphyrin and LDL showed competitive conjugation with the LDL receptor. These results support the theory of the porphyrin uptake via the LDL receptor.
摘要
我们使用流式细胞术（FCM）检测了四种已建立的胶质瘤细胞系和正常成纤维细胞对卟啉和低密度脂蛋白（LDL）的同时摄取情况。结果表明，卟啉和LDL与LDL受体表现出竞争性结合。这些结果支持了通过LDL受体摄取卟啉的理论。
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