Xu B, Pekkanen J, Hartikainen A L, Järvelin M R
Department of Epidemiology and Public Health, Imperial College School of Medicine, Norfolk Place W2 1PG, London, UK.
J Allergy Clin Immunol. 2001 Apr;107(4):732-3. doi: 10.1067/mai.2001.113048.
This study evaluated the relationship of caesarean section to the risk of asthma in adulthood. The data were based on a prospective birth cohort born in northern Finland in 1966. In 1997, when the members of the cohort were 31 years old, information on current doctor-diagnosed asthma and other allergic disorders was obtained from 1953 subjects by a self-administered questionnaire and skin prick test. Caesarean section had a strong effect on current doctor-diagnosed asthma in adulthood with an adjusted odds ratio (OR) of 3.23 (95% CI 1.53, 6.80). However, no substantial effects were observed for atopy, hay fever, and atopic eczema.
本研究评估了剖宫产与成年后患哮喘风险之间的关系。数据基于1966年出生在芬兰北部的一个前瞻性出生队列。1997年,当该队列成员31岁时,通过自填问卷和皮肤点刺试验从1953名受试者中获取了当前医生诊断的哮喘及其他过敏性疾病的信息。剖宫产对成年后当前医生诊断的哮喘有强烈影响,调整后的优势比(OR)为3.23(95%置信区间1.53, 6.80)。然而,对于特应性、花粉症和特应性皮炎未观察到实质性影响。