Brown M M, Brown G C, Sharma S, Busbee B, Brown H
Center for Evidence-Based Health Care Economics, 1107 Bethlehem Pike, Suite 210, Flourtown, PA 19031, USA.
Ophthalmology. 2001 Apr;108(4):643-7; discussion 647-8. doi: 10.1016/s0161-6420(00)00635-7.
To ascertain with patient preference-based methodology whether individuals with good visual acuity (20/20-20/25) in one eye have the same quality of life as individuals with good vision in both eyes.
Cross-sectional comparative study.
Consecutive patients seen in comprehensive ophthalmic and vitreoretinal practices with known ocular disease and good visual acuity (20/20 or 20/25) in one or both eyes.
Standardized patient interview.
Time tradeoff and utility analysis values.
The mean time tradeoff utility value in 81 patients with good visual acuity in one eye was 0.89 (standard deviation, 0.17; 95% confidence interval, 0.85-0.93), whereas the mean value in 66 patients with good vision in both eyes was 0.97 (standard deviation, 0.05; 95% confidence interval, 0.97-0.99). The difference between the means of the utility values in these two groups was significant using multiple linear regression (P = 0.001).
From the patient preference-based point of view, individuals with ocular disease and good visual acuity in both eyes appear to have a higher time tradeoff utility value, and thus a better associated quality of life, than those with good visual acuity in only one eye.
采用基于患者偏好的方法,确定单眼视力良好(20/20 - 20/25)的个体与双眼视力良好的个体是否具有相同的生活质量。
横断面比较研究。
在综合眼科和玻璃体视网膜科就诊的连续性患者,患有已知眼病,单眼或双眼视力良好(20/20或20/25)。
标准化患者访谈。
时间权衡和效用分析值。
81名单眼视力良好患者的平均时间权衡效用值为0.89(标准差,0.17;95%置信区间,0.85 - 0.93),而66名双眼视力良好患者的平均值为0.97(标准差,0.05;95%置信区间,0.97 - 0.99)。使用多元线性回归分析,这两组效用值均值之间的差异具有统计学意义(P = 0.001)。
从基于患者偏好的角度来看,患有眼病且双眼视力良好的个体似乎比仅单眼视力良好的个体具有更高的时间权衡效用值,因此生活质量更好。